Jianguo Xu Selected Research

Neuroinflammatory Diseases

1/2021	Hyperoside Attenuate Inflammation in HT22 Cells via Upregulating SIRT1 to Activities Wnt/β-Catenin and Sonic Hedgehog Pathways.
1/2021	Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
10/2020	Methylene blue post-treatment improves hypoxia-ischemic recovery in a neonatal rat model.
6/2020	Luteolin alleviates neuroinflammation via downregulating the TLR4/TRAF6/NF-κB pathway after intracerebral hemorrhage.
10/2014	Melatonin reduced microglial activation and alleviated neuroinflammation induced neuron degeneration in experimental traumatic brain injury: Possible involvement of mTOR pathway.
8/2010	Repeated administration of pioglitazone attenuates development of hyperalgesia in a rat model of neuropathic pain.
2/2007	Pentoxifylline attenuates the development of hyperalgesia in a rat model of neuropathic pain.

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Jianguo Xu Research Topics

Disease

72	Neoplasms (Cancer) 03/2024 - 04/2002
22	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2024 - 01/2013
20	Infections 05/2024 - 11/2005
19	Sepsis (Septicemia) 01/2022 - 01/2002
17	Inflammation (Inflammations) 03/2024 - 08/2005
15	Glioma (Gliomas) 08/2023 - 09/2013
15	Neuralgia (Stump Neuralgia) 01/2021 - 08/2003
14	Lung Injury 01/2024 - 02/2005
14	Glioblastoma (Glioblastoma Multiforme) 01/2023 - 08/2014
12	Craniopharyngioma (Craniopharyngiomas) 01/2023 - 01/2006
12	Hyperalgesia 09/2014 - 01/2006
10	Brain Injuries (Brain Injury) 12/2023 - 06/2014
10	Wounds and Injuries (Trauma) 10/2023 - 08/2010
8	Neoplasm Metastasis (Metastasis) 01/2024 - 12/2010
8	Fibrosis (Cirrhosis) 02/2023 - 08/2005
7	COVID-19 01/2024 - 01/2021
7	Brain Edema (Cerebral Edema) 01/2022 - 08/2010
7	Pain (Aches) 01/2022 - 01/2006
7	Neuroinflammatory Diseases 01/2021 - 02/2007
6	Melanoma (Melanoma, Malignant) 11/2023 - 09/2009
6	Acute Lung Injury 11/2023 - 02/2005
6	Necrosis 01/2020 - 04/2006
5	Hepatocellular Carcinoma (Hepatoma) 10/2023 - 04/2019
5	Pneumonia (Pneumonitis) 01/2023 - 09/2006
5	Cerebral Hemorrhage 01/2021 - 08/2018
4	Ischemic Stroke 02/2024 - 01/2018
4	Gestational Diabetes (Gestational Diabetes Mellitus) 08/2023 - 10/2016
4	Carcinogenesis 01/2023 - 08/2014
4	Central Serous Chorioretinopathy 01/2023 - 01/2021
4	Brain Neoplasms (Brain Tumor) 01/2023 - 02/2012
4	Stroke (Strokes) 10/2021 - 11/2016
4	Brain Ischemia (Cerebral Ischemia) 01/2017 - 12/2008
4	Weight Loss (Weight Reduction) 01/2016 - 08/2010
3	Human Influenza (Influenza) 05/2024 - 08/2012
3	Hyperplasia 02/2024 - 11/2005
3	Leukemia 12/2023 - 09/2009
3	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 08/2023 - 01/2022
3	Fever (Fevers) 01/2023 - 11/2008
3	Epilepsy (Aura) 02/2022 - 09/2011
3	Colitis 01/2022 - 04/2002
3	Meningioma (Meningiomas) 01/2022 - 09/2014
3	Ischemia 10/2021 - 01/2006
3	Hypoxia (Hypoxemia) 10/2020 - 01/2014

Drug/Important Bio-Agent (IBA)

28	Proteins (Proteins, Gene)FDA Link 01/2024 - 04/2002
28	CytokinesIBA 01/2023 - 01/2002
19	Biomarkers (Surrogate Marker)IBA 04/2024 - 04/2014
16	MicroRNAs (MicroRNA)IBA 01/2024 - 07/2018
16	NF-kappa B (NF-kB)IBA 08/2017 - 01/2005
12	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2024 - 01/2002
11	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2002
10	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 06/2007
9	EnzymesIBA 10/2023 - 04/2006
9	Messenger RNA (mRNA)IBA 06/2020 - 01/2002
8	Bleomycin (Blenoxane)FDA LinkGeneric 11/2012 - 08/2005
7	Neuroprotective AgentsIBA 03/2024 - 01/2013
6	RNA (Ribonucleic Acid)IBA 03/2024 - 06/2012
6	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 12/2021
6	AntigensIBA 01/2020 - 04/2002
5	CateninsIBA 10/2023 - 12/2015
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2021 - 01/2006
5	Phosphotransferases (Kinase)IBA 01/2021 - 01/2014
5	salicylhydroxamic acid (SHAM)IBA 02/2015 - 01/2007
5	Interleukin-10 (Interleukin 10)IBA 08/2013 - 01/2006
4	Peptides (Polypeptides)IBA 02/2024 - 04/2014
4	Nucleic AcidsIBA 03/2023 - 01/2016
4	Erythropoietin FDA Link 01/2023 - 04/2006
4	VaccinesIBA 01/2021 - 02/2010
4	AntibodiesIBA 10/2020 - 11/2008
4	LuteolinIBA 06/2020 - 06/2014
4	Therapeutic UsesIBA 01/2020 - 08/2002
4	LipopolysaccharidesIBA 01/2020 - 01/2003
4	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 07/2015 - 07/2014
4	Starch (Cornstarch)IBA 08/2010 - 01/2005
4	HES 130-0.4IBA 08/2010 - 09/2006
4	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 12/2008 - 03/2006
4	Pentoxifylline (Trental)FDA LinkGeneric 02/2008 - 01/2006
3	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 12/2023 - 12/2021
3	Hemoglobins (Hemoglobin)IBA 10/2023 - 07/2020
3	GoldIBA 01/2023 - 04/2002
3	LipidsIBA 01/2023 - 11/2020
3	Immune Checkpoint InhibitorsIBA 01/2023 - 01/2021
3	Blood Glucose (Blood Sugar)IBA 01/2022 - 08/2017
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 01/2020
3	Hyaluronic Acid (Hyaluronan)IBA 04/2021 - 12/2011
3	CreatinineIBA 01/2021 - 04/2002
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2018
3	Chimeric Antigen ReceptorsIBA 01/2021 - 01/2020
3	Caspase 3 (Caspase-3)IBA 01/2021 - 06/2007
3	fibrin fragment D (D-dimer)IBA 01/2019 - 01/2018

Therapy/Procedure

35	Therapeutics 03/2024 - 04/2002
9	Ligation 01/2020 - 01/2007
8	Immunotherapy 11/2023 - 01/2020
7	Drug Therapy (Chemotherapy) 11/2023 - 10/2016
5	Negative-Pressure Wound Therapy 10/2023 - 11/2018
5	Radiotherapy 01/2021 - 11/2012
5	Punctures 01/2020 - 01/2007
4	Craniotomy 01/2022 - 02/2012
4	Aftercare (After-Treatment) 01/2021 - 08/2010
3	Lasers (Laser) 01/2023 - 06/2021
3	Laser Therapy (Surgery, Laser) 01/2022 - 01/2021